The Jacksonville Jaguars (6-4) are looking for their fourth win in a row this week and will facing off against the San Francisco 49ers (4-6).  The Jaguars’ offense has been doing a good job taking care of the ball and that is the main reason they have a three game winning streak.  Quarterback David Garrard only has one interception during that streak, and if he can continue to be smart with the ball the Jaguars will have a great shot at winning this one.  Maurice Jones-Drew is going to play through a knee injury and should still be very effective against a 49ers defense that has been struggling against the run lately.  If Jones-Drew’s knee is bothering him a lot though, the Jaguars may be in some trouble.

The Jaguars’ defense needs to get some turnovers and do their best to limit running back Frank Gore.  Gore is averaging 5.4 yards per carry this season, but he doesn’t get much help from his quarterbacks.  Alex Smith has started the last five games for the Niners and has thrown at least one interception in every one.  Smith’s inconsistency will likely continue and I think this will give the Jaguars the edge.  I think the Jaguars will win the turnover battle and thus win the game because of it.

FINAL SCORE PREDICTION:  Jacksonville Jaguars 24, San Francisco 49ers 21